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Evaluation and Treatment of Prediabetes in Youth

Sheela N. Magge, Janet Silverstein, Deborah Elder, Kristen Nadeau and Tamara S. Hannon. The Journal of Pediatrics, April,Volume 219, Pages 11–22

The increased prevalence of pediatric obesity has led to an increased incidence and prevalence of type 2 diabetes mellitus (T2DM), as well as the intermediate condition of prediabetes, in youth. Given that the definitions for these conditions were established based on adult data, pediatric providers are struggling with the definition and significance of prediabetes in children.
Although this report addresses prediabetes as a precursor to T2DM in the child and adolescent with overweight/obese child, type 1 diabetes remains the most common cause of diabetes during childhood, and should be kept under consideration by the clinician regardless of the child’s body mass index (BMI). This is particularly true in youth less than 10 years of age and/or who are prepubertal.