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Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland

On 5 April 2022, WHO was notified of 10 cases of severe acute hepatitis of unknown aetiology in children under the age of 10 years, across central Scotland. By 8 April, 74 cases had been identified in the United Kingdom. Hepatitis viruses (A, B, C, E, and D where applicable) have been excluded after laboratory testing while further investigations are ongoing to understand the aetiology of these cases. Given the increase in cases reported over the past one month and enhanced case search activities, more cases are likely to be reported in the coming days.